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Test Code MYPPC Cytogenetics (Fluorescence In-situ Hybridisation) (Expanded MM FISH Panel on targeted plasma cells)

Important Note

**Refer to Flow Chart for ordering guide**

Specimen Requirements

Fresh specimen required

 

(A) Specimen Type: Bone marrow 
      Container/Tube: Green Top (Sodium Heparin)
      Volume: 1-2mL

 

(B) Specimen Type: Peripheral Blood
      Container/Tube: Green Top (Sodium Heparin)
      Volume: 4-8mL, preferably presence of >5% blasts

 

(C) Specimen Type: Lymph Node / Solid Tumour /Bone core
      Container: Sterile tube with 3ml collection media.
(Prearrange with Cytogenetics Laboratory for collection media)

 

(D)  Specimen Type: Effusions (CSF, Pleural Effusion etc)
      Container: Sterile universal container
      Volume: 3-6mL,preferably presence of >10% cells


Additional Collection Instructions: All specimens should be shipped to the lab within 12-24 hours of collection. Specimen received after 48 hours of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.

Days and Times Performed

Monday through Friday (Office hours only). TAT 1-2 weeks

Methodology

Fluorescence In-situ hybridisation.

Service Code

1680009, 1680010

Update

Last updated 23/10/2024

Added Test Info

Specimen Stability

** Preferred temperatures for storage prior to and during shipping to NUH **

 

Fresh specimen required.

Ambient, upt to 48 hours

Reference

An interpretative report will be provided.

Testing Laboratory

National University Hospital
Cytogenetics, 67722512

Useful For

Detection of chromosomal abnormalities in Multiple Myeloma (MM) for t(4;14), t(11;14), t(14;16), deletion and duplication of 1p/1q, deletion of LSI D13S319, monosomy 13 and deletion of LSI TP53.  Refer to Table 2 .

Test Info

This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.

 

Reagent(s) used in this test is/are ordered through HSA’s Special Access Route, which provides interim access without full registration.

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