Test Code MDSP Cytogenetics (Fluorescence In-situ Hybridisation) (MDS FISH Panel)
Specimen Requirements
Submit one of the following:
Fresh specimen required
(A) Specimen Type: Bone marrow
Container/Tube: Green Top (Sodium Heparin)
Volume: 1-2mL
(B) Specimen Type: Peripheral Blood
Container/Tube: Green Top (Sodium Heparin)
Volume: 4-8mL, preferably presence of >5% blasts
(C) Specimen Type: Lymph Node / Solid Tumour /Bone core
Container: Sterile tube with 3ml collection media.
(Prearrange with Cytogenetics Laboratory for collection media)
(D) Specimen Type: Effusions (CSF, Pleural Effusion etc)
Container: Sterile universal container
Volume: 3-6mL,preferably presence of >10% cells
Additional Collection Instructions: All specimens should be shipped to the lab within 12-24 hours of collection. Specimen received after 48 hours of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.
Days and Times Performed
Monday through Friday (Office hours only). TAT 1-2 weeks
Methodology
Fluorescence In-situ hybridisation.
Service Code
1680007
Update
Last updated 23/10/2024
Added Test Info
Specimen Stability
** Preferred temperatures for storage prior to and during shipping to NUH **
Fresh specimen required
Ambient (Preferred): | 12 hours |
---|---|
Refrigerate: | 12 – 48 hours |
Reference
An interpretative report will be provided.
Testing Laboratory
National University Hospital
Cytogenetics, 67722512
Useful For
Detection of chromosomal abnormalities in Myelodysplastic Syndrome (MDS) for deletion of 5q, 7q, monosomy 7, deletion of 20q and trisomy 8. Refer to Table 2 .
Test Info
This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.
Reagent(s) used in this test is/are ordered through HSA’s Special Access Route, which provides interim access without full registration.
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- Cytogenetics (Fluorescence In-situ Hybridisation) (FISH Interphase for 1 probe - IFISH)
- Cytogenetics (Fluorescence In-situ Hybridisation) (FISH Interphase for 2 probes – IF2P)
- Cytogenetics (Fluorescence In-situ Hybridisation) (FISH Interphase for 3 probes – IF3P)
- Cytogenetics (Fluorescence In-situ Hybridisation) (FISH Add-on for 1 probe - AFISH)
- Cytogenetics (Fluorescence In-situ Hybridisation) (FISH Add-on for any 2 probes – AF2P)
- Cytogenetics (Fluorescence In-situ Hybridisation) (FISH Add-on for 3 probes – AF3P)