Sign in →

Test Code CLLP Cytogenetics (Fluorescence In-situ Hybridisation) (CLL FISH Panel)

Important Note

**Refer to Flow Chart for ordering guide**

Specimen Requirements

Submit one of the following:

 

Fresh specimen required

 

(A) Specimen Type: Bone marrow 
      Container/Tube: Green Top (Sodium Heparin)
      Volume: 1-2mL

 

(B) Specimen Type: Peripheral Blood
      Container/Tube: Green Top (Sodium Heparin)
      Volume: 4-8mL, preferably presence of >5% blasts

 

(C) Specimen Type: Lymph Node / Solid Tumour /Bone core
      Container: Sterile tube with 3ml collection media.
(Prearrange with Cytogenetics Laboratory for collection media)

 

(D)  Specimen Type: Effusions (CSF, Pleural Effusion etc)
      Container: Sterile universal container
      Volume: 3-6mL,preferably presence of >10% cells

 

Additional Collection Instructions: All specimens should be shipped to the lab within 12-24 hours of collection. Specimen received after 48 hours of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.

Days and Times Performed

Monday through Friday(Office hours only). TAT 1-2 weeks

Methodology

Fluorescence In-situ hybridisation.

Service Code

1680006

Update

Last updated 23/10/2024

Added Test Info

Specimen Stability

** Preferred temperatures for storage prior to and during shipping to NUH **

 

Fresh specimen required

Ambient (Preferred): 12 hours
Refrigerate: 12 – 48 hours

 

Reference

An interpretative report will be provided.

Testing Laboratory

National University Hospital
Cytogenetics, 67722512

Useful For

Detection of chromosomal abnormalities in Chronic Lymphocytic Leukemia (CLL) for deletion of LSI ATM, LSI D13S319, monosomy 13, deletion of LSI TP53 and gain of D12Z3. Refer to Table 2 .

Test Info

This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.

 

Reagent(s) used in this test is/are ordered through HSA’s Special Access Route, which provides interim access without full registration.

Related Tests