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Test Code CLLP Cytogenetics (Fluorescence In-situ Hybridisation) (CLL FISH Panel)

Important Note

Refer to Flow Chart for ordering guide.

All specimens should be shipped to the lab within 12 - 24 hours of collection. Specimen received after 48 hours of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.

Additional Codes

EPIC Ordering Code LAB3040674
NBS Code LBC01057
Service Code 1680006

 

Specimen Requirements

Submit one of the following:

 

Fresh specimen required

 

For (A) and (B)

Preferred: Acceptable:
Green top (Na Heparin) Green top (Li Heparin)

(A) Specimen Type: Bone Marrow 
      Volume: 1.0 - 2.0 mL
      Storage/transport requirement: Ambient

 

(B) Specimen Type: Peripheral Blood
      Volume: 4.0 - 8.0 mL, preferably presence of > 5% blasts
      Storage/transport requirement: Ambient

 

(C) Specimen Type: Lymph Node / Solid Tumour / Bone core
      Container: Sterile tube with 3.0 mL collection media
      Storage/transport requirements:  Ambient                                                                         (Prearrange with Cytogenetics Laboratory for collection media).

    

For (D):

Preferred:
Sterile Universal Container

(D)  Specimen Type: Effusions (CSF, Pleural Effusion etc)
       Volume: 3.0 - 6.0mL,preferably presence of > 10% cells
       Storage/transport requirement: Ambient

Specimen Stability

Fresh specimen required

Ambient 12 hours (Preferred)
Refrigerate 12 - 48 hours

 

Specimen Condition

Blood 

Haemolysis Alert
Icterus OK
Gross Lipaemia OK
Others (Clotted or Frozen) Reject

Bone Marrow/Effusions

Haemolysis Alert
Icterus OK
Gross Lipaemia OK
Others (Clotted or Frozen) Reject

Lymph Node / Solid Tumour / Bone Core

Haemolysis Not applicable
Icterus Not applicable
Gross Lipaemia Not applicable
Others (Frozen, air-dry or formalin fixed tissue) Reject

 

Methodology

Fluorescence In-situ hybridisation.

Days and Times Performed

Monday through Saturday (Office hours only). TAT 21 days, STAT 7-14 days

Reference Interval

An interpretative report will be provided.

Testing Laboratory

National University Hospital
Cytogenetics, 67722512

Useful For

Detection of chromosomal abnormalities in Chronic Lymphocytic Leukemia (CLL) for deletion of LSI ATM, LSI D13S319, monosomy 13, deletion of LSI TP53 and gain of D12Z3. Refer to Table 2 .

Update

Last updated 09/06//2026

LOINC Code Information

82256-9

Test Info

This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.

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