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Test Code AMLNG Myeloid Neoplasm NGS Panel for Acute Myeloid Leukemia (AML)

Important Note

Completion of General Consent Form is required for this test. Please submit the completed form along with the sample request form.

Additional Codes

Epic Ordering Code LAB3041864
NBS code LBC08394
Service code 1035095

Specimen Requirements

Submit the following: 

 

Preferred:

Purple Top

Processing Requirements

Specimen type: Whole Blood or Bone Marrow Aspirate

Volume: 3.0 mL (at least 1.0 mL for bone marrow aspirate)

Storage/transport requirements: Ambient or refrigerated

Specimen Stability

Specimen Type Whole Blood or Bone Marrow Aspirate
Ambient 7 days
Refrigerate 7 days

Specimen Condition

Frozen Reject
Haemolysis Reject

Methodology

Next-generation sequencing

Days and Times Performed

TAT 3 - 4 weeks

Reference Interval

An interpretive report will be provided.

Testing Laboratory

National University Hospital
Genomics Diagnostic Laboratory, 67724384

Useful For

For acute myeloid leukemia (AML) with panel included:

ABL1, ANKRD26, ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CBLB, CBLC, CDKN2A, CEBPA, CSF3R, DDX41, DNMT3A, ELANE, ETNK1, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, KDM6A, KIT, KRAS, MLL, MPL, NF1, NPM1, NRAS, PDGFRA, PHF6, PPM1D, PTEN, PTPN11, RAD21, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, STAT3, TET2, TP53, U2AF1, UBA1, UBTF, WT1, ZRSR2

The following additional test will also be performed: Fragment analysis for the FLT3 gene, enabling detection of both internal tandem duplications and mutations in the tyrosine kinase domain.

Update

Last updated 15/06/2026

Test Info

(a)  This test was developed by NUH Laboratory Medicine.

(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.