Test Code AMLNG Myeloid Neoplasm NGS Panel for Acute Myeloid Leukemia (AML)
Laboratory Code
LAB3041864
Specimen Requirements
Specimen Type: Whole Blood or Bone Marrow Aspirate
Container/Tube: Lavender Top (EDTA)
Specimen Volume: 3.0 mL x 1 tube
Specimen Stability
7 days, ambient or refrigerated
Methodology
Next-generation sequencing
Days and Times Performed
TAT 3 - 4 weeks
Specimen Condition
Frozen or hemolysis - Reject
Reference Interval
An interpretive report will be provided.
Testing Laboratory
National University Hospital
Molecular Diagnosis Centre, 67724384
Useful For
For acute myeloid leukemia (AML) with panel included:
ABL1, ANKRD26, ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CBLB, CBLC, CDKN2A, CEBPA, CSF3R, DDX41, DNMT3A, ELANE, ETNK1, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, KDM6A, KIT, KRAS, MLL, MPL, NF1, NPM1, NRAS, PDGFRA, PHF6, PPM1D, PTEN, PTPN11, RAD21, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, STAT3, TET2, TP53, U2AF1, UBA1, UBTF, WT1, ZRSR2
The following additional test will also be performed: Fragment analysis for the FLT3 gene, enabling detection of both internal tandem duplications and mutations in the tyrosine kinase domain.
Service Code
1035095
Update
Last updated 23/04/2025
Test Info
(a) This test was developed by NUH Laboratory Medicine.
(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.