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HelpTest Code CML ABL1 Kinase domain mutation screen
Specimen Requirements
Specimen Type: Whole blood or bone marrow
aspirate
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3mL (at least 1mL for bone marrow
aspirate)
Days and Times Performed
Bimonthly, TAT 14 working days.
Methodology
Reverse Transcription Polymerase Chain Reaction, DNA sequencing
Service Code
1035070
Update
Last updated 25/02/2020
Specimen Stability
72 hours, ambient or refrigerated (preferably ambient)
Testing Laboratory
National University Hospital
Molecular Diagnosis Centre, 67724384
Useful For
Identifies ABL1 mutations resulting in possible treatment resistance in chronic myeloid leukemia and other Philadelphia chromosome positive-hematological malignancies
Reference
An interpretative report will be provided.