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HelpTest Code CML ABL1 Kinase domain mutation screen
Laboratory Code
LAB3041101
Specimen Requirements
Specimen Type: Whole blood or bone marrow aspirate
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3mL (at least 1mL for bone marrow aspirate)
Specimen Stability
72 hours, ambient or refrigerated (preferably ambient)
Methodology
Reverse Transcription Polymerase Chain Reaction, DNA sequencing
Days and Times Performed
TAT 1 month
Reference Interval
An interpretative report will be provided.
Useful For
Identifies ABL1 mutations resulting in possible treatment resistance in chronic myeloid leukemia and other Philadelphia chromosome positive-hematological malignancies
Service Code
1035070
Update
Last updated 04/07/2025
Referring/Testing Laboratory
National University Hospital
Molecular Diagnosis Centre, 67724384
Testing Laboratory
Singapore General Hospital
Haematology Laboratory (Molecular), 63214722