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Test Code MPNNG Myeloid Neoplasm NGS Panel for Myeloproliferative Neoplasm (MPN)

Additional Codes

Epic Ordering Code NA
NBS code LBC08395
Service code 1035094

Specimen Requirements

Submit the following: 

 

Preferred:

Purple Top

 

Collection Instructions: Completion of General Consent Form is required for this test. Please submit the completed form along with the sample request form.

Processing Requirements

Specimen type: Whole Blood or Bone Marrow Aspirate

Volume: 3.0 mL (at least 1.0 mL for bone marrow aspirate)

Storage/transport requirements: Ambient or refrigerated

Specimen Stability

Specimen Type Whole Blood or Bone Marrow Aspirate
Ambient 3 days
Refrigerate 7 days

Specimen Condition

Clotted, Haemolysed, Frozen Reject
Anticoagulant other than EDTA Reject
Improperly labelled specimen Reject

Methodology

Next-generation sequencing

Days and Times Performed

TAT 3 - 4 weeks

Reference Interval

An interpretive report will be provided.

Testing Laboratory

National University Hospital
Genomics Diagnostic Laboratory, 67724384

Useful For

For myeloproliferative neoplasm (MPN) with panel included:

ABL1, ANKRD26, ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CBLB, CBLC, CDKN2A, CEBPA, CSF3R, DDX41, DNMT3A, ELANE, ETNK1, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, KDM6A, KIT, KRAS, MLL, MPL, NF1, NPM1, NRAS, PDGFRA, PHF6, PPM1D, PTEN, PTPN11, RAD21, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, STAT3, TET2, TP53, U2AF1, UBA1, UBTF, WT1, ZRSR2

The following additional test will also be performed: Fragment analysis for the CALR gene, enabling detection of large insertions and deletions.

Update

Last updated 10/07/2026

Test Info

(a)  This test was developed by NUH Laboratory Medicine.

(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.