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Test Code MPNNG Myeloid Neoplasm NGS Panel for Myeloproliferative Neoplasm (MPN)

Important Note

Completion of General Consent Form is required for this test. Please submit the completed form along with the sample request form.

Additional Codes

Epic Ordering Code NA
NBS code LBC08395
Service code 1035094

Specimen Requirements

Submit the following: 

 

Preferred:

Purple Top

Processing Requirements

Specimen type: Whole Blood or Bone Marrow Aspirate

Volume: 3.0 mL (at least 1.0 mL for bone marrow aspirate)

Storage/transport requirements: Ambient or refrigerated

Specimen Stability

Specimen Type Whole Blood or Bone Marrow Aspirate
Ambient 7 days
Refrigerate 7 days

Specimen Condition

Frozen Reject
Haemolysis Reject

Methodology

Next-generation sequencing

Days and Times Performed

TAT 3 - 4 weeks

Reference Interval

An interpretive report will be provided.

Testing Laboratory

National University Hospital
Genomics Diagnostic Laboratory, 67724384

Useful For

For myeloproliferative neoplasm (MPN) with panel included:

ABL1, ANKRD26, ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CBLB, CBLC, CDKN2A, CEBPA, CSF3R, DDX41, DNMT3A, ELANE, ETNK1, ETV6, EZH2, FLT3, GATA1, GATA2, GNAS, HRAS, IDH1, IDH2, JAK2, KDM6A, KIT, KRAS, MLL, MPL, NF1, NPM1, NRAS, PDGFRA, PHF6, PPM1D, PTEN, PTPN11, RAD21, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, STAT3, TET2, TP53, U2AF1, UBA1, UBTF, WT1, ZRSR2

The following additional test will also be performed: Fragment analysis for the CALR gene, enabling detection of large insertions and deletions.

Update

Last updated 11/06/2026

Test Info

(a)  This test was developed by NUH Laboratory Medicine.

(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.