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Test Code 8BM19 Flow Cytometry - BCP-ALL MRD panel post anti-CD19 immunotherapy

Important Note

Please provide relevant treatment history including monoclonal antibody treatment (e.g. anti-CD19, anti-CD20 and anti-CD22 treatment, etc.) on test request form.

 

Testing is performed on fresh sample and samples should be dispatched to reach the laboratory before 2pm Monday to Friday for processing. As such, do not dispatch samples on eve of Public Holiday, Saturday and Sunday.

 

Refer to FCM Flow Chart for ordering guide

Laboratory Code

LAB3052987

Specimen Requirements

Submit one of the following:

 

Fresh specimen required

 

(a) Specimen Type: Bone Marrow (preferable)

      Container/Tube: Lavender Top (EDTA), Green Top (Sodium Heparin)

      Preferred Volume: 5.0 mL

 

(b) Specimen Type: Peripheral Blood

      Container/Tube: Lavender Top (EDTA), Green Top (Sodium Heparin)

      Preferred Volume: 10.0 mL

      Collection Instructions: Collect 20.0 mL blood if WBC < 5 x 109/L.

 

Additional Collection Instructions: All specimens should be shipped to the lab in ambient temperature (18 - 25oC) within 24 - 48 hrs of collection. Specimen received after 48 hrs of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.

Specimen Stability

Fresh specimen required

Ambient 24 hours (preferred)
Refrigerate 48 hours

Methodology

Flow Cytometry

Days and Times Performed

Monday through Friday. TAT 14 - 16 days (STAT 7 - 9 days)

Reference Interval

See laboratory report

Testing Laboratory

National University Hospital
Flow Cytometry, 67724016

Useful For

This panel is used for follow-up examination of B-ALL post anti-CD19 immunotherapy or CAR-T treatment. The previously detected characteristic aberrant expressions are used for MRD monitoring.

Service Code

12666

Update

Last updated 08/01/2025

Unacceptable Condition

Specimen Type
Bone Marrow/Peripheral Blood Frozen              

Test Info

Pre-arrange with Haematology before ordering the test.

 

This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.

 

Reagent(s) used in this test is/are ordered through HSA’s Special Access Route, which provides interim access without full registration.