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HelpTest Code BRFM BRAF mutation detection
Specimen Requirements
Preferred:
Specimen Type: Whole blood or bone marrow
aspirate
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3mL x 2 for whole blood or at
least 1mL for bone marrow aspirate
Acceptable:
Specimen Type: Other body fluid
Container/Tube: Sterile plain
container
Specimen Volume: Entire collection
Days and Times Performed
Bimonthly, TAT 14 working days.
Methodology
Polymerase Chain Reaction, DNA Sequencing
Service Code
1035071
Update
Last updated 25/02/2020
Testing Laboratory
National University Hospital
Molecular Diagnosis Centre, 67724384
Useful For
BRAF Val600Glu (V600E) mutation detection aids in identifying colon tumours with a previously negative KRAS mutation analysis result that may respond to EGFR-targeted therapies. This test aids in identifying melanoma tumours that may respond to anti-BRAF targeted thereapies. It aids in diagnosis of papillary thyroid carcinoma or anaplastic thyroid carcinoma in fine-needle aspirate specimens
Reference
An interpretative report will be provided.