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Test Code 8PCDD Flow Cytometry - Myeloma / Plasma Cell Dyscrasia Panel (Diagnostic)

Important Note

Please provide analysis results of immunoglobulin light chain in multiple myeloma and plasma cell dyscrasias, and relevant treatment history including monoclonal antibody treatment (e.g. anti-CD19 and anti-CD38 treatment, etc.) on test request form.

 

Testing is performed on fresh sample and samples should be dispatched to reach the laboratory before 2pm Monday to Friday for processing. As such, do not dispatch samples on eve of Public Holiday, Saturday and Sunday.

 

Refer to FCM Flow Chart for ordering guide

Laboratory Code

LAB3041881

Specimen Requirements

Submit one of the following:

 

Fresh specimen required

 

(a) Specimen Type: Bone Marrow (preferable)

      Container/Tube: Lavender Top (EDTA), Green Top (Sodium Heparin)

      Preferred Volume: 5.0 - 10.0 mL

 

(b) Specimen Type: Peripheral Blood

      Container/Tube: Lavender Top (EDTA), Green Top (Sodium Heparin)

      Preferred Volume: 20.0 mL

 

(c) Specimen Type: Lymph Node / Solid Tumour

      Container/Tube: Sterile container with 5.0 mL RPMI 1640 media

      Preferred Volume: 5 mm(3) or larger biopsy

      Collection Instructions: Place tissue directly into 5.0 mL RPMI 1640 media after biopsy.

      Do not leave tissue to air-dry or fix tissue in formalin.

      (Prearrange with Flow Cytometry Laboratory for transport media prior sample collection)

     

(d) Specimen Type: Body Fluid

      Container/Tube: Sterile tube with 0.6 mL transfix media

      Preferred Volume: 3.0 - 6.0 mL

      (Prearrange with Flow Cytometry Laboratory for transport media prior sample collection)

           

Additional Collection Instructions: All specimens should be shipped to the lab in ambient temperature (18 - 25oC) within 24 - 48 hrs of collection. Specimen received after 48 hrs of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.

Specimen Stability

Fresh specimen required

Ambient 24 hours (preferred)
Refrigerate 48 hours             

Methodology

Flow Cytometry

Days and Times Performed

Monday through Friday. TAT 14 - 16 days (STAT 7 - 9 days)

Reference Interval

See laboratory report

Testing Laboratory

National University Hospital
Flow Cytometry, 67724016

Useful For

This panel is used to diagnose multiple myeloma, various subtypes of plasma cell dyscrasia and amyloidosis. Patient with characteristic aberrant expressions may be followed up as MRD monitoring.

Service Code

12670

Update

Last updated 08/01/2025

Unacceptable Condition

Specimen Type
Bone Marrow/Peripheral Blood Frozen                     

Test Info

Pre-arrange with Haematology before ordering the test.

 

This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.

 

Reagent(s) used in this test is/are ordered through HSA’s Special Access Route, which provides interim access without full registration.