Test Code TRYPT Tryptase, Serum
Additional Codes
| Epic Ordering Code | LAB2410 |
| NBS code | LBC13389 |
| Service code | 36652 |
Reporting Name
Tryptase, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
Additional Information: Tryptase degenerates very quickly when left in the presence of red blood cells.
NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Yellow Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen ype: Serum
Volume: 0.5 mL
Storage/transport requirements: Refrigerated
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.
Special Instructions
Specimen Minimum Volume
0.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen (preferred) | 14 days |
| Refrigerated | 7 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Fluorescence Enzyme Immunoassay (FEIA)
Testing Algorithm
For more information see Mast Cell Disorder: Diagnostic Algorithm, Bone Marrow.
Day(s) Performed
Monday through Friday
Report Available
2 to 5 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
<11.5 ng/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Evaluation of individuals with suspected mast cell activation, which may occur as a result of anaphylaxis or allergen challenge
Evaluation of patients with suspected mast cell activation syndrome
Evaluation of patients with suspected cutaneous or systemic mastocytosis
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TRYPT | Tryptase, S | 21582-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TRYPT | Tryptase, S | 21582-2 |
CPT Code Information
83520
Secondary ID
81608Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Last updated 07/08/2026