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Test Code TB4 TB Quantiferon

Specimen Requirements

Specimen Type: Whole Blood
Container/Tube: Green Top (Li Heparin)
Volume: 4.0mL tube (2 full tubes)
Minimum Volume: Whole blood, 5.0 mL (2 full tubes)

Collection Instructions: 

Kindly ensure specimen reach NUH Laboratory by 3pm on the same day of collection on Mondays to Thursdays ONLY. Specimens will not be accepted on Fridays, Saturdays, Sundays, eve of public holidays and on public holidays. 

 

Sample Stability

** Preferred temperatures for storage prior to and during shipping to NUH **

 

Specimen Type: Whole Blood
Ambient: 16 hours
Refrigerate: NA
Frozen: NA

 

Reference Interval

Negative

Days and Times Performed

Friday, TAT 2-8 days

Methodology

Enzyme Immunoassay

Service Code

0032148

Update

Last updated 16/02/2024

Updated on collection instructions.

Unacceptable Condition

 

Haemolysis NA
Icterus NA
Lipaemic NA
Others Samples that arrive at laboratory > 16 hours after collection. Samples dispatched on eve of Public Holiday, Saturday and Sunday.

 

Testing Laboratory

National University Hospital
Clinical Chemistry, 67724346

Alias

Interferon-gamma, QuantiFERON-TB Gold Plus

Useful For

It can be used as an aid in diagnosing Mycobacterium tuberculosis infection, including both latent tuberculosis infection (LTBI) and tuberculosis (TB) disease. This enzyme-linked immunosorbent assay test detects the release of interferon-gamma in fresh heparinized whole blood from sensitized persons when it is incubated with mixtures of synthetic peptides simulating two proteins present in M. tuberculosis: early secretory antigenic target-6 (ESAT-6) and culture filtrate protein-10 (CFP-10). ESAT-6 and CFP-10 are secreted by all M. tuberculosis and pathogenic M. bovis strains. These proteins are absent from all Bacille Calmette-Guerin (BCG) vaccine strains and from commonly encountered non-tuberculous mycobacteria (NTM).