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Test Code SYPS Syphilis Screen

Laboratory Code

LAB3040198

Specimen Requirements

Specimen Type: Serum
Container/Tube: Gold Top (SSTII) / Red Top
Volume: 5.0 mL / 6.0 mL blood
Minimum Volume: 0.5 mL serum
Collection Instructions: Allow specimen to clot for 30 mins and centrifuge within 2 hrs

Specimen Stability

Specimen Type Serum
Ambient 3 days
Refrigerate 7 days (preferred)
Frozen 1 year 

Methodology

Chemiluminescent Immunoassay

Days and Times Performed

Monday through Friday, TAT 1 - 5 days

TPPA and RPR: Tuesday and Friday, TAT 1 - 5 days

Specimen Condition

Gross Haemolysis Reject
Icterus OK
Lipaemia OK
Others Not applicable

Reference Interval

Non-reactive 

 

Confirmatory / Reflex information:

Test name Reference Interval Critical Value
Treponema pallidum Passive Particle Agglutination Non-reactive Not applicable
Rapid Plasma Reagin < 1:2  > 1:2 (NUH Antenatal Screen only)

Reflex Testing

Samples reactive for Syphilis Ab are confirmed by supplemental test Treponema pallidum Passive Particle Agglutination (TPPA) Assay. 

Samples reactive for TPPA are tested by a supplemental test Rapid Plasma Reagin (RPR) to confirm an acute syphilis (For NUH and AH only).

Testing Laboratory

National University Hospital

Clinical Chemistry, 67724346

Useful For

Screening test for current or previous syphilis infection

Service Code

31858

LOINC Code Information

24110-9

 

Confirmatory / Reflex tests:

Treponema Pallidum Particle Agglutination (TPPA) 24312-1
Rapid Plasma Reagin Value 31147-2
Rapid Plasma Reagin 20507-0

Alias

Syphilis Antibody

Syphilis Serology

Update

Last updated 21/02/2025