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Test Code SYPS Syphilis Screen

Additional Codes

Epic Ordering Code LAB3040198
NBS code LBC00952
Service code 31858

Specimen Requirements

Submit only one of the following:

Preferred: Acceptable:
Yellow Top Red Top

Processing Requirements

Allow specimen to clot for 30 mins and centrifuge within 2 hours

Specimen type: Serum

Volume: 0.5mL

Specimen Stability

Specimen Type Serum
Ambient 3 days
Refrigerate 7 days (preferred)
Frozen 1 year 

Specimen Condition

Gross Haemolysis Reject
Icterus OK
Lipaemia OK
Others Not applicable

Methodology

Chemiluminescent Immunoassay

Days and Times Performed

Monday through Friday, TAT 1 - 5 days

TPPA and RPR: Tuesday and Friday, TAT 1 - 5 days

Reference Interval

Non-reactive 

 

Confirmatory / Reflex information:

Test name Reference Interval Critical Value
Treponema pallidum Passive Particle Agglutination Non-reactive Not applicable
Rapid Plasma Reagin < 1:2  > 1:2 (NUH Antenatal Screen only)

Testing Laboratory

National University Hospital

Clinical Chemistry, 67724346

Useful For

Screening test for current or previous syphilis infection

Update

Last updated 26/07/2026

LOINC Code Information

24110-9

 

Confirmatory / Reflex tests:

Treponema Pallidum Particle Agglutination (TPPA) 24312-1
Rapid Plasma Reagin Value 31147-2
Rapid Plasma Reagin 20507-0

Alias

Syphilis Antibody

Syphilis Serology

Reflex Testing

Samples reactive for Syphilis Ab are confirmed by supplemental test Treponema pallidum Passive Particle Agglutination (TPPA) Assay. 

Samples reactive for TPPA are tested by a supplemental test Rapid Plasma Reagin (RPR) to confirm an acute syphilis (For NUH and AH only).