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HelpTest Code SYPS Syphilis Screen
Specimen Requirements
Specimen Type: Serum
Container/Tube: Gold Top (SSTII) / Red Top
Volume: 5.0 mL / 6.0 mL blood
Minimum Volume: 0.5 mL serum
Collection Instructions: Allow specimen to clot for 30 mins and centrifuge within 2 hrs
Specimen Stability
| Specimen Type | Serum |
|---|---|
| Ambient | 3 days |
| Refrigerate | 7 days (preferred) |
| Frozen | 1 year |
Specimen Condition
| Gross Haemolysis | Reject |
|---|---|
| Icterus | OK |
| Lipaemia | OK |
| Others | Not applicable |
Methodology
Chemiluminescent Immunoassay
Days and Times Performed
Monday through Friday, TAT 1 - 5 days
TPPA and RPR: Tuesday and Friday, TAT 1 - 5 days
Reference Interval
Non-reactive
Confirmatory / Reflex information:
| Test name | Reference Interval | Critical Value |
|---|---|---|
| Treponema pallidum Passive Particle Agglutination | Non-reactive | Not applicable |
| Rapid Plasma Reagin | < 1:2 | > 1:2 (NUH Antenatal Screen only) |
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724346
Useful For
Screening test for current or previous syphilis infection
Service Code
31858
Update
Last updated 21/02/2025
Alias
Syphilis Antibody
Syphilis Serology
Laboratory Code
LAB3040198
LOINC Code Information
24110-9
Confirmatory / Reflex tests:
| Treponema Pallidum Particle Agglutination (TPPA) | 24312-1 |
|---|---|
| Rapid Plasma Reagin Value | 31147-2 |
| Rapid Plasma Reagin | 20507-0 |
Reflex Testing
Samples reactive for Syphilis Ab are confirmed by supplemental test Treponema pallidum Passive Particle Agglutination (TPPA) Assay.
Samples reactive for TPPA are tested by a supplemental test Rapid Plasma Reagin (RPR) to confirm an acute syphilis (For NUH and AH only).