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HelpTest Code SYPS Syphilis Screen
Specimen Requirements
Specimen Type: Serum
Container/Tube: Gold Top (SSTII) / Red Top
Volume: 5.0 mL / 6.0 mL blood
Minimum Volume: 0.5 mL serum
Collection Instructions: Allow specimen to clot for 30 mins and centrifuge within 2 hrs
Specimen Stability
| Specimen Type | Serum |
|---|---|
| Ambient | 3 days |
| Refrigerate | 7 days (preferred) |
| Frozen | 1 year |
Specimen Condition
| Gross Haemolysis | Reject |
|---|---|
| Icterus | OK |
| Lipaemia | OK |
| Others | Not applicable |
Methodology
Chemiluminescent Immunoassay
Days and Times Performed
Monday through Friday, TAT 1 - 5 days
TPPA and RPR: Tuesday and Friday, TAT 1 - 5 days
Reference Interval
Non-reactive
Confirmatory / Reflex information:
| Test name | Reference Interval | Critical Value |
|---|---|---|
| Treponema pallidum Passive Particle Agglutination | Non-reactive | Not applicable |
| Rapid Plasma Reagin | < 1:2 | > 1:2 (NUH Antenatal Screen only) |
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724346
Useful For
Screening test for current or previous syphilis infection
Update
Last updated 21/02/2025
Alias
Syphilis Antibody
Syphilis Serology
LOINC Code Information
24110-9
Confirmatory / Reflex tests:
| Treponema Pallidum Particle Agglutination (TPPA) | 24312-1 |
|---|---|
| Rapid Plasma Reagin Value | 31147-2 |
| Rapid Plasma Reagin | 20507-0 |
Service Code
31858
Laboratory Code
LAB3040198
Reflex Testing
Samples reactive for Syphilis Ab are confirmed by supplemental test Treponema pallidum Passive Particle Agglutination (TPPA) Assay.
Samples reactive for TPPA are tested by a supplemental test Rapid Plasma Reagin (RPR) to confirm an acute syphilis (For NUH and AH only).