Test Code SIL2R Interleukin-2 Receptor Alpha Soluble, Plasma
Additional Codes
| Epic Ordering Code | LAB3041926 |
| NBS code | LBC11787 |
| Service code | 37118 |
Reporting Name
IL-2 receptor alpha soluble, PSpecimen Type
Plasma EDTAOrdering Guidance
If this test is ordered with CYPAN / Cytokine Panel, Plasma, this test will be canceled as duplicate and CYPAN performed as ordered.
If this test is ordered with CYTH1 / T-Helper Cell Type 1 Cytokine Panel, Plasma, this test will be canceled as duplicate and CYTH1 performed as ordered.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Lavender-top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Immediately after specimen collection, place tube on wet ice.
2. Centrifuge at 4° C, 1500 x g for 10 minutes.
3. Aliquot plasma a into plastic vial.
4. Freeze specimen within 2 hours of collection.
Additional Information:
If a refrigerated centrifuge is not available, it is acceptable to use a room temperature centrifuge, provided the sample is kept on ice before centrifugation and is frozen immediately afterward.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma EDTA | Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-treated specimen | Reject |
Method Name
Bead-Based Multiplex Immunoassay
Day(s) Performed
Thursday
Report Available
2 to 8 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
<18 years: Not established
≥18 years: <959 pg/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Measuring the concentration of soluble interleukin-2 receptor alpha (sIL-2r alpha) in plasma
Aids in the diagnosis and evaluation of patients for lymphoproliferative disorders, including autoimmune lymphoproliferative syndrome, hemophagocytic lymphohistiocytosis, and macrophage activation syndrome
May help monitor patients with sarcoidosis or hematologic malignancies with elevated sIL-2r alpha
CPT Code Information
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SIL2R | IL-2 receptor alpha soluble, P | 76039-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 622328 | IL-2 receptor alpha soluble | 76039-7 |
Secondary ID
622328Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Last updated 27/07/2026