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Test Code RIVA Rivaroxaban Anti-Xa

Important Note

For peak level, collect specimen after 2 - 4 hours of drug administration; for trough level, collect specimen before administering the next dose.

In single or multiple dosing, the time interval between specimen collection and administration of dose must be specified.

Additional Codes

Epic Ordering Code LAB3040080
NBS code LBC00093
Service code 12507

Specimen Requirements

Submit the following: 

 

Preferred:
Light Blue Top

Processing Requirements

Specimen Type: Whole Blood
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Volume: 2 × 2.7 mL Whole Blood (Tubes must be full)

Collection Instructions: Send whole blood specimens to laboratory immediately.

 

Specimen Type: Platelet Poor Plasma
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Submission Container/Tube: Plastic Vial
Minimum Volume: 1.0 mL Plasma
Collection Instructions:
1. Light blue top tube must be properly filled with whole blood.
2. Whole blood specimen should be double centrifuged and plasma separated from cells within 1 hr of collection.
3. Plasma should be separated into 2 aliquots with minimum volume of 1.0 mL each.
4. Freeze the aliquots in well-closed plastic tubes immediately.

Specimen Stability

Specimen Type Plasma
Ambient 8 hours
Refrigerate 8 hours
Frozen 30 days (preferred)

Specimen Condition

Haemolysis Gross reject
Icterus Gross reject
Lipaemia Gross reject
Others: Clotted or insufficient Reject

Methodology

Chromogenic Assay

Days and Times Performed

24 hrs, TAT 1 day

Reference Interval

Clinical interpretive report will be provided.

Testing Laboratory

National University Hospital, Singapore
Haematology, 67722323

Useful For

Monitoring of Rivaroxaban therapy

Update

Last updated 22/06/2026

Alias

Rivaroxaban

Xarelto®