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Test Code PMET Metanephrines, fractionated, free, plasma

Additional Codes

Epic Ordering Code LAB2402
NBS code LBC13406
Service code 33421

Specimen Requirements

Submit the following:                                               

Container/Tube: Purple

 

Patient should be relaxed in a seated or supine position 30 mins before blood is drawn. Overnight fasting preferred, patient should avoid caffeine/nicotine/alcohol and strenuous exercise 12 hrs prior to blood draw.

Processing Requirements

Centrifuge within 1 hour

Specimen type: Plasma

Volume: 1.5 mL

Storage/transport requirements: Frozen

 

Centrifuge and separate the plasma within 1 hr of collection. Separated plasma should be stored frozen.

Specimen Stability

Specimen Type  Plasma EDTA
Ambient 6 hours
Refrigerate 10 days
Frozen 14 days (preferred)

Specimen Condition

Haemolysis OK
Icterus OK
Lipaemia OK
Others Not applicable

Methodology

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Days and Times Performed

Monday and Thursday, TAT 3 - 9 days

Reference Interval

Seated Reference Interval:

Normetanephrine, Free: ≤ 1180 pmol/L

Metanephrine, Free: ≤ 510 pmol/L

 

Supine Reference Interval:

Normetanephrine, Free: ≤ 953 pmol/L

Metanephrine, Free: ≤ 371 pmol/L

Testing Laboratory

National University Hospital

Clinical Chemistry, 67728489

Useful For

Screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas.

Update

Last updated 10/04/2026

Test Classification

This test was developed by NUH Laboratory Medicine. This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.

 

Reagents used in this test are ordered through HSA’s Special Access Route, which provides interim access without full registration.