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Test Code PK1 Pyruvate Kinase Enzyme Activity, Blood

Additional Codes

Epic Ordering Code LAB3041498
NBS code LBC11742
Service code 36713

Reporting Name

PK Enzyme Activity, B

Specimen Type

Whole Blood ACD-B


Specimen Required


Container/Tube:

Preferred: Yellow top (ACD solution B)

Acceptable: Lavender top (EDTA)

Specimen Volume: 6 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: ACD Tube (Solution B)
Acceptable: Purple Top
Processing Requirements
Send whole blood specimen in original tube. Do not aliquot.
Specimen type: Whole Blood
Volume: 6 mL
Storage/transport requirements: Refrigerated

Forms

If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood ACD-B Refrigerated 20 days

Reject Due To

Gross hemolysis Reject
Fully clotted Reject

Method Name

Kinetic Spectrophotometry (KS)

Day(s) Performed

Monday through Friday

Report Available

1 to 4 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

≥12 months of age: 5.5-12.4 U/g Hb

 

Reference values have not been established for patients younger than 12 months.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of nonspherocytic hemolytic anemia

 

Evaluation of neonatal anemia or jaundice

 

Evaluation of unexplained noninfectious hepatic failure

 

Evaluation of unexplained iron overload

 

Evaluation of unusually severe hemoglobin S trait

 

Evaluation of unusually severe glucose 6-phosphate dehydrogenase deficiency

 

Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling

CPT Code Information

84220

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PK1 PK Enzyme Activity, B 32552-2

 

Result ID Test Result Name Result LOINC Value
PKCL PK Enzyme Activity, B 32552-2

Secondary ID

607459

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
National University Hospital-Singapore Additional Information:

Last updated 05/08/2026