Sign in →

Test Code PHNB Phenobarbital

Laboratory Code

LAB30

Specimen Requirements

Submit only one of the following:
 

Preferred
Specimen Type: Serum
Container/Tube: Gold Top (SSTII) 
Volume: 5.0 mL 
Minimum Volume: 0.5 mL serum
Collection Instructions: Allow specimen to clot for 30 mins and centrifuge within 2 hrs.

 

Acceptable
Specimen Type: Plasma
Container/Tube: Green Top (Li Heparin/PST)
Volume: 4.5 mL
Minimum Volume: 0.5 mL plasma
Collection Instructions: Centrifuge within 2 hrs.

Specimen Stability

Specimen Type Serum/Plasma
Ambient 7 days
Refrigerate 6 months
Frozen 6 months

Methodology

Particle-Enhanced Turbidimetric Inhibition Immunoassay (PETINIA)

Days and Times Performed

24 hrs, TAT 1 day

Specimen Condition

Haemolysis OK
Icterus OK
Lipaemia OK
Others Not applicable

Reference Interval

The desired therapeutic effect is usually achieved in the serum concentration range of 15 to 40 mg/L. Concentrations of 35 to 80 mg/L are associated with slowness, ataxia, and nystagmus. 

Concentrations of 65 to 117 mg/L are associated with coma with reflexes. 

Concentrations > 100 mg/L are associated with coma without reflexes.

 

Critical value: > 40 mg/L

Testing Laboratory

National University Hospital

Clinical Chemistry, 67724346

Useful For

Therapeutic drug monitoring.

Service Code

31821

LOINC Code Information

3948-7

Alias

Phenobarbitone

Update

Last updated 12/03/2025