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HelpTest Code PHNB Phenobarbital
Specimen Requirements
Submit only one of the followings
Preferred
Specimen Type: Serum
Container/Tube: Gold Top (SSTII)
Volume: 5.0mL
Minimum Volume: 0.5mL serum
Collection Instructions: Allow specimen to clot for 30 minutes and centrifuge within 2 hours
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Acceptable
Specimen Type: Plasma
Container/Tube: Green Top (Li Heparin/PST)
Volume: 4.5mL
Minimum Volume: 0.5mL plasma
Collection Instructions: Centrifuge within 2 hours
Sample Stability
** Preferred temperatures for storage prior to and during shipping to NUH **
| Specimen Type: | Serum/Plasma |
|---|---|
| Ambient: | 7 days |
| Refrigerate: | 6 months |
| Frozen: | 6 months |
Reference Interval
Critical: >40 mg/L
The desired therapeutic effect is usually achieved in the serum concentration range of 15 to 40 mg/L. Concentrations of 35 to 80 mg/L are associated with slowness, ataxia, and nystagmus.
Concentrations of 65 to 117 mg/L are associated with coma with reflexes.
Concentrations > 100 mg/L are associated with coma without reflexes
Days and Times Performed
24 hours, TAT 1 day
Methodology
Particle-enhanced turbidimetric inhibition immunoassay (PETINIA)
Service Code
31821
Update
Last updated 26/02/2022
Unacceptable Condition
| Haemolysis | NA |
|---|---|
| Icterus | NA |
| Lipaemic | NA |
| Others | NA |
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724346
Useful For
Therapeutic drug monitoring
Alias
Phenobarbitone