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Test Code PCYG Cytogenetics (Constitutional Chromosomal Karyotyping)

Important Note

Refer to Flow Chart for ordering guide

Informed Consent Form for Prenatal and Postnatal Chromosomal Karyotyping/FISH is required.

Specimen Requirements

Submit one of the following:

 

Fresh specimen required

 

(A) Specimen Type: Amniotic Fluid

      Container: Sterile Universal Container

      Volume: 20.0 mL


(B) Specimen Type: Chorionic Villi

      Container: Sterile tube with 10.0 mL collection media.

      Amount: ~25.0 mg

(Prearrange with Cytogenetics Laboratory for collection media)


(C) Specimen Type: Foetal Blood

      Container: Green Top (Sodium Heparin)

      Volume: 1.0 - 2.0 mL
 

(D) Specimen Type: Peripheral Blood

      Container: Green Top (Sodium Heparin)

      Volume: 4.0 mL

 

(E) Specimen Type: Cord Blood

      Container: Green Top (Sodium Heparin)

      Volume: 4.0 mL

 

(F) Specimen Type: Product of Conception [villi from placenta (preferred), achilles tendon or skin]

      Container: Sterile tube with 10.0 mL collection media.

(Prearrange with Cytogenetics Laboratory for collection media)

 

(G) Specimen Type: Skin Biopsy / Other Tissues

      Container: Sterile tube with 10.0 mL collection media.

(Prearrange with Cytogenetics Laboratory for collection media)

 

Additional Collection Instructions: All specimens should be shipped to the lab within 12 - 24 hours of collection. Specimen received after 48 hours of collection will nonetheless be processed but results may be compromised. For overseas specimens, avoid shipping on Friday or eve of public holidays.

Specimen Stability

Fresh specimen required

Specimen Type Ambient Refrigerate
Amniotic Fluid 12 – 48 hours –
Chorionic Villi 12 hours (preferred) 12 – 48 hours
Foetal Blood 12 hours (preferred) 12 – 48 hours
Peripheral Blood 12 hours (preferred) 12 – 48 hours
Cord Blood 12 hours (preferred) 12 – 48 hours
Product of Conception 12 hours (preferred) 12 – 48 hours
Skin Biopsy / Other Tissues 12 hours (preferred) 12 – 48 hours

 

 

 

 

 

 

 

 

 

Methodology

Cell culture followed by chromosome analysis.

Days and Times Performed

Monday through Saturday (Office hours only).

 

Specimen Type TAT
Amniotic Fluid / Chorionic Villi 10 – 14 days
Foetal Blood / Cord Blood 10 – 14 days
Peripheral Blood  21 – 28 days
Product of Conception 10 – 14 days
Skin Biopsy / Other Tissues 6 weeks

 

 

 

 

 

 

 

Reference Interval

An interpretative report will be provided.

Testing Laboratory

National University Hospital
Cytogenetics, 67722512

Useful For

Detection of structural and numerical chromosome abnormalities.

Service Code

1682103

Update

Last updated 28/03/2023

Unacceptable Condition

Specimen Type  
Foetal Blood / Peripheral Blood / Cord Blood Frozen, or collected in EDTA tube
Skin Biopsy / Other Tissues Frozen, or formalin fixed tissues

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