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HelpTest Code PCA Anti-Parietal Cell Antibody
Specimen Requirements
Specimen Type: Serum
Container/Tube: Gold Top (SSTII) / Red Top
Volume: 5.0mL / 6.0mL blood
Minimum Volume: 0.5mL serum
Collection Instructions: Allow specimen to clot for 30 minutes and centrifuge within 2 hours
Sample Stability
** Preferred temperatures for storage prior to and during shipping to NUH **
| Specimen Type: | Serum |
|---|---|
| Ambient: | 2 days |
| Refrigerate: | 2 weeks |
| Frozen: | 1 year |
Reference Interval
No antibody detected: <20 U/mL
Positive: ≥ 20 U/mL
Days and Times Performed
Monday, TAT 2-8 days
Methodology
Enzyme Immunoassay
Service Code
0032140
Update
last updated 26/02/2022
Unacceptable Condition
| Haemolysis: | NA |
|---|---|
| Icterus: | NA |
| Lipaemic: | NA |
| Others: | NA |
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724346
Useful For
Useful in diagnosis of pernicious anaemia, where – 80% of patients demonstrate antibody positivity. A positive test in the presence of a megaloblastic anaemia makes pernicious anaemia a probable diagnosis. A negative test will help differentiate pernicious anaemia from other anaemias and Whipple’s disease. Positive antibody titres can also be seen in gastritis, gastric ulcer, gastric cancer, chronic thyroiditis, iron deficient anaemia, juvenile diabetes mellitus, idiopathic Addison’s disease and normal individuals.
Alias
PCA, Parietal Cell Ab