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Test Code NSE Neuron-Specific Enolase, Serum

Important Note


SAMPLE ONLY HAS 7 DAYS STABILITY TO REACH MAYO LABORATORIES - REFERRING HOSPITAL LABORATORY SHOULD CONTACT NUH LABORATORY FOR FEASIBILITY.

Do not collect specimen on Fridays through Sundays, eve of public holidays and public holidays.

Specimens should not be transported by tube system prior to centrifugation.
 

Additional Codes

Epic Ordering Code LAB3040394
NBS code LBC08568
Service code 36937

Reporting Name

Neuron Specific Enolase, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Specimens should not be transported by tube system prior to centrifugation.

2. Centrifuge and aliquot serum into a plastic vial.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Red Top
Acceptable: Yellow Top
Specimens should not be transported by tube system prior to centrifugation.
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Refrigerated

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Ambient  5 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject
Hemolysis at any level Reject

Method Name

Homogeneous Time-Resolved Fluorescence

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

≤15 ng/mL

Serum markers are not specific for malignancy, and values may vary by method.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type

 

An auxiliary test in the diagnosis of small cell lung carcinoma

 

An auxiliary test in the diagnosis of carcinoids, islet cell tumors, and neuroblastomas

 

An auxiliary tool in the assessment of comatose patients

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NSE Neuron Specific Enolase, S 15060-7

 

Result ID Test Result Name Result LOINC Value
NSE Neuron Specific Enolase, S 15060-7

Secondary ID

80913

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
National University Hospital-Singapore Additional Information:

Last updated 04/08/2026