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Test Code MYD88 MYD88 L265P Mutation Detection

Specimen Requirements

Preferred:

Specimen Type: Whole blood or bone marrow aspirate
Container/Tube: Lavender top (EDTA)
Specimen Volume: For whole blood please send 4 tubes (3mL each); for bone marrow aspirate please send 1 tube (3mL).

 

Acceptable:

Specimen Type: Tissue sections
Container/Tube: Slides (uncoated)
Specimen Quantity: One H&E and five unstained sections of 10 micron thickness

 

Specimen Type: Cerebrospinal fluid (CSF)
Container/Tube: Sterile plain container
Specimen Quantity: Entire collection

Days and Times Performed

Weekly, TAT 14 working days

Methodology

Allele-specific polymerase chain reaction (AS-PCR)

Service Code

1035086

Update

Last updated 07/08/2024

Specimen Stability

7 days, ambient or refrigerated for whole blood, bone marrow aspirate, or cerebrospinal fluid (CSF)

Testing Laboratory

National University Hospital
Molecular Diagnosis Centre, 67724384

Useful For

Detection of MYD88 L265P mutation aids in the distinction of Waldenstrom Macroglobulinemia (WM) or lymphoplasmacytic lymphoma (LPL) from Marginal zone lymphomas (MZLs), IgM-secreting myeloma (MM), and chronic lymphocytic leukemia (CLL).

Reference

An interpretative report will be provided.