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HelpTest Code MYD88 MYD88 L265P Mutation Detection
Additional Codes
| Epic Ordering Code | LAB3040410 |
| NBS code | LBC13209 |
| Service code | 1035086 |
Specimen Requirements
Submit only one of the following:
| Preferred: | Acceptable: | Acceptable: | |
| Purple Top | Sterile Container | Slides | |
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Processing Requirements
Specimen type: Whole Blood or Bone Marrow Aspirate (in Purple Top EDTA tube)
Volume: For whole blood, please send 4 tubes (3 mL each), for bone marrow aspirate, please send 1 tube (3 mL)
Storage/transport requirements: Ambient or Refrigerated
Specimen type: Cerebrospinal Fluid (CSF) (in Sterile Container)
Volume: Whole collection (at least 0.5 mL)
Storage/transport requirements: Ambient or Refrigerated
Specimen type: Eye aqueous and vitreous (in Sterile Container)
Volume: Whole collection (at least 0.5 mL)
Storage/transport requirements: Ambient or Refrigerated
Specimen type: Tissue sections (on Slides (uncoated))
Quantity: One H&E and five unstained sections of 10 micron thickness
Storage/transport requirements: Ambient or Refrigerated
Specimen Stability
| Specimen Type | Whole Blood or Bone Marrow Aspirate |
| Ambient | 3 days |
| Refrigerate | 7 days |
Specimen Condition
| Clotted, Haemolysed, Frozen Blood or Bone Marrow Aspirate | Reject |
| Anticoagulant other than EDTA for Blood or Bone Marrow Aspirate | Reject |
| Improperly labelled specimen | Reject |
| Insufficient volume of specimen | Reject |
Methodology
Allele-specific polymerase chain reaction (AS-PCR)
Days and Times Performed
TAT 20 days
Reference Interval
An interpretative report will be provided.
Testing Laboratory
National University Hospital
Genomics Diagnostic Laboratory, 67724384
Useful For
Detection of MYD88 L265P mutation aids in the distinction of Waldenstrom Macroglobulinemia (WM) or lymphoplasmacytic lymphoma (LPL) from Marginal zone lymphomas (MZLs), IgM-secreting myeloma (MM), and chronic lymphocytic leukemia (CLL).
Update
Last updated 11/06/2026
Test Info
(a) This test was developed by NUH Laboratory Medicine.
(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.