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Test Code MYD88 MYD88 L265P Mutation Detection

Laboratory Code

LAB3040410

Specimen Requirements

Preferred

Specimen Type: Whole Blood or Bone Marrow Aspirate
Container/Tube: Lavender top (EDTA)
Specimen Volume: For whole blood, please send 4 tubes (3 mL each), for bone marrow aspirate, please send 1 tube (3 mL)

 

Acceptable

Specimen Type: Tissue sections
Container/Tube: Slides (uncoated)
Specimen Quantity: One H&E and five unstained sections of 10 micron thickness

 

Specimen Type: Cerebrospinal Fluid (CSF)
Container/Tube: Sterile plain container
Specimen Quantity: Entire collection

 

Specimen Type: Eye aqueous and vitreous
Container/Tube: Sterile plain container
Specimen Quantity: Entire collection

 

Specimen Stability

7 days, ambient or refrigerated for whole blood, bone marrow aspirate, or cerebrospinal fluid (CSF)

Methodology

Allele-specific polymerase chain reaction (AS-PCR)

Days and Times Performed

TAT 20 days

Reference Interval

An interpretative report will be provided.

Testing Laboratory

National University Hospital
Molecular Diagnosis Centre, 67724384

Useful For

Detection of MYD88 L265P mutation aids in the distinction of Waldenstrom Macroglobulinemia (WM) or lymphoplasmacytic lymphoma (LPL) from Marginal zone lymphomas (MZLs), IgM-secreting myeloma (MM), and chronic lymphocytic leukemia (CLL).

Service Code

1035086

Update

Last updated 20/03/2025

Test Info

(a)  This test was developed by NUH Laboratory Medicine.

(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements.