Test Code LYME Lyme Disease Serology, Serum
Additional Codes
| Epic Ordering Code | LAB3040958 |
| NBS code | LBC12889 |
| Service code | 36889 |
Reporting Name
Lyme Disease Serology, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Information: Centrifuge and aliquot serum into plastic vial.
NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Gold Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Frozen
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 10 days |
| Frozen | 30 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat inactivated | Reject |
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Algorithm
If Lyme disease serology is positive or equivocal, then Lyme disease antibody confirmation (by Western blot) will be performed at an additional charge.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| LYWB | Lyme Disease Ab, Immunoblot, S | Yes | No |
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
Negative
Reference values apply to all ages.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Diagnosing Lyme disease
This test should not be used as a screening procedure for the general population.
This test should not be used for treatment monitoring.
CPT Code Information
86618
86617 x 2-Lyme disease confirmation (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LYME | Lyme Disease Serology, S | 20449-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| LYME | Lyme Disease Serology, S | 20449-5 |
Secondary ID
9129Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Last updated 03/07/2026