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Test Code LUPS Lupus Anticoagulant Screen

Important Note

For patient receiving anticoagulant treatment: Lupus anticoagulant testing in patients on anticoagulation may give rise to false-positive or false-negative result.

Laboratory Code

LAB3001

Specimen Requirements

Submit only one of the following specimens


Specimen Type: Whole Blood
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Volume: 2 × 2.7 mL whole blood (Tubes must be full)
Collection Instructions: Send whole blood specimens to laboratory immediately.


Specimen Type: Platelet Poor Plasma
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Submission Container/Tube: Plastic Vial

Minimum Volume: 2.0 mL plasma
Collection Instructions:
1. Light blue top tube must be properly filled with whole blood.

2. Whole blood specimen should be double centrifuged and plasma separated from cells within 1 hr of collection.
3. Plasma should be separated into 2 aliquots with minimum volume of 1.0 mL each.
4. Freeze the aliquots in well-closed plastic tubes immediately.

Specimen Stability

Specimen Type Plasma
Ambient 4 hours
Refrigerate Not available
Frozen 14 days (preferred)

Panel Information

Panel includes the following tests:

Methodology

Viscosity-Based Clot Detection

Days and Times Performed

Monday through Friday, TAT 14 days

Specimen Condition

Gross Haemolysis Reject
Gross Icterus Reject
Gross Lipaemia Reject
Others: Clotted or insufficient specimen Reject

Reference Interval

Absent

Testing Laboratory

National University Hospital
Haematology, 67725320

Useful For

Detects the presence of lupus anticoagulant, a phospholipid inhibitor. Consider this test in unexplained prolongation of APTT, recurrent abortions, thrombocytopenia or systemic lupus erythematosus.

Service Code

12414

LOINC Code Information

PT 5902-2
INR 6301-6
APTT 14979-9
LUPUS ANTICOAGULANT 75514-0
APTT(1+1) CORRECTION 5946-9
CONTROL PLASMA 13488-2

 

Alias

Lupus Anticoagulant

LA Sensitive PTT
Dilute Russell’s Viper Venom Test

DRVVT

Update

Last updated 21/03/2025

Reflex Tests

  • APTT mixing study if APTT is > 40.0 seconds
  • Staclot LA