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Test Code LUPS Lupus Anticoagulant Screen

Important Note

Please ensure that patient is NOT on any anticoagulant therapy prior to blood collection.

Specimen Requirements

Submit only one of the following specimens


Specimen Type: Whole Blood
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Volume: 2 × 2.7mL Whole Blood (Tubes must be full)
Collection Instructions: Send whole blood specimens to laboratory immediately.


Specimen Type: Platelet Poor Plasma
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Submission Container/Tube: Plastic Vial

Minimum Volume: 2.0mL Plasma
Collection Instructions:
1. Light blue top tube must be properly filled with whole blood.

2. Whole blood specimen should be double centrifuged and plasma separated from cells within 1 hour of collection.
3. Plasma should be separated into 2 aliquots with minimum volume of 1mL each.
4. Freeze the aliquots in well-closed plastic tubes immediately.

Reference Interval

Absent

Days and Times Performed

Monday through Friday, TAT 10 working days

Methodology

Viscosity-Based Clot Detection

Service Code

12414

Update

Last updated 25/02/2020

Unacceptable Condition

Haemolysis Gross reject
Icterus Gross reject
Lipaemic Gross reject
Others Clotted or insufficient reject

 

Specimen Stability

**Preferred temperatures for storage prior to and during shipping to NUH**

 

Specimen Type Plasma
Ambient 4 hours
Refrigerate NA
Frozen 14 days

 

Testing Laboratory

National University Hospital
Haematology, 67725320

Useful For

Detects the presence of lupus anticoagulant, a phospholipid inhibitor. Consider this test in unexplained prolongation of APTT, recurrent abortions, thrombocytopenia or systemic lupus erythematosus.

Profile Information

  • Prothrombin Time
  • Activated Partial Thromboplastin Time
  • LA Sensitive PTT
  • Dilute Russell’s Viper Venom Test

Reflex Tests

  • APTT mixing study if APTT is > 40.0 seconds
  • Staclot LA

Alias

Lupus Anticoagulant

LA Sensitive PTT
Dilute Russell’s Viper Venom Test

DRVVT