Test Code LUPS Lupus Anticoagulant Screen
Laboratory Code
LAB3001
Specimen Requirements
Submit only one of the following specimens
Specimen Type: Whole Blood
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Volume: 2 × 2.7 mL whole blood (Tubes must be full)
Collection Instructions: Send whole blood specimens to laboratory immediately.
Specimen Type: Platelet Poor Plasma
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Submission Container/Tube: Plastic Vial
Minimum Volume: 2.0 mL plasma
Collection Instructions:
1. Light blue top tube must be properly filled with whole blood.
2. Whole blood specimen should be double centrifuged and plasma separated from cells within 1 hr of collection.
3. Plasma should be separated into 2 aliquots with minimum volume of 1.0 mL each.
4. Freeze the aliquots in well-closed plastic tubes immediately.
Specimen Stability
| Specimen Type | Plasma |
|---|---|
| Ambient | 4 hours |
| Refrigerate | Not available |
| Frozen | 14 days (preferred) |
Panel Information
Panel includes the following tests:
- Prothrombin Time
- Activated Partial Thromboplastin Time
- LA Sensitive PTT
- Dilute Russell’s Viper Venom Test
Methodology
Viscosity-Based Clot Detection
Days and Times Performed
Monday through Friday, TAT 14 days
Specimen Condition
| Gross Haemolysis | Reject |
|---|---|
| Gross Icterus | Reject |
| Gross Lipaemia | Reject |
| Others: Clotted or insufficient specimen | Reject |
Reference Interval
Absent
Testing Laboratory
National University Hospital
Haematology, 67725320
Useful For
Detects the presence of lupus anticoagulant, a phospholipid inhibitor. Consider this test in unexplained prolongation of APTT, recurrent abortions, thrombocytopenia or systemic lupus erythematosus.
Service Code
12414
LOINC Code Information
| PT | 5902-2 |
|---|---|
| INR | 6301-6 |
| APTT | 14979-9 |
| LUPUS ANTICOAGULANT | 75514-0 |
| APTT(1+1) CORRECTION | 5946-9 |
| CONTROL PLASMA | 13488-2 |
Alias
Lupus Anticoagulant
LA Sensitive PTT
Dilute Russell’s Viper Venom Test
DRVVT
Update
Last updated 21/03/2025
Reflex Tests
- APTT mixing study if APTT is > 37.0 seconds
- Staclot LA