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Test Code LUPS Lupus Anticoagulant Screen

Important Note

For patient receiving anticoagulant treatment: Lupus anticoagulant testing in patients on anticoagulation may give rise to false-positive or false-negative result.

Specimen Requirements

Submit only one of the following specimens


Specimen Type: Whole Blood
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Volume: 2 × 2.7 mL whole blood (Tubes must be full)
Collection Instructions: Send whole blood specimens to laboratory immediately.


Specimen Type: Platelet Poor Plasma
Container/Tube: 2 Light Blue Top (3.2% Sodium Citrate)
Submission Container/Tube: Plastic Vial

Minimum Volume: 2.0 mL plasma
Collection Instructions:
1. Light blue top tube must be properly filled with whole blood.

2. Whole blood specimen should be double centrifuged and plasma separated from cells within 1 hr of collection.
3. Plasma should be separated into 2 aliquots with minimum volume of 1.0 mL each.
4. Freeze the aliquots in well-closed plastic tubes immediately.

Specimen Stability

Specimen Type Plasma
Ambient 4 hours
Refrigerate Not available
Frozen 14 days (preferred)

Specimen Condition

Gross Haemolysis Reject
Gross Icterus Reject
Gross Lipaemia Reject
Others: Clotted or insufficient specimen Reject

Methodology

Photo-optical Clot Detection

Days and Times Performed

Monday through Friday, Office hours, TAT 10 days

Reference Interval

Absent

Testing Laboratory

National University Hospital
Haematology, 67725320

Useful For

Detects the presence of lupus anticoagulant, a phospholipid inhibitor. Consider this test in unexplained prolongation of APTT, recurrent abortions, thrombocytopenia or systemic lupus erythematosus.

Service Code

12414

Update

Last updated 14/01/2026

Panel Information

Panel includes the following tests:

Reflex Tests

  • APTT mixing study if APTT is > 37.0 seconds
  • Staclot LA

Alias

Lupus Anticoagulant

LA Sensitive PTT
Dilute Russell’s Viper Venom Test

DRVVT

Laboratory Code

LAB3001

LOINC Code Information

PT 5902-2
INR 6301-6
APTT 14979-9
LUPUS ANTICOAGULANT 75514-0
APTT(1+1) CORRECTION 5946-9
CONTROL PLASMA 13488-2