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Test Code LAMO Lamotrigine, Serum

Additional Codes

Epic Ordering Code LAB3040469
NBS code LBC07461
Service code 36914

Reporting Name

Lamotrigine, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Collect blood immediately before next scheduled dose.

2. Only for sustained-release formulations, collect blood a minimum of 12 hours after last dose.

3. Within 2 hours of collection, centrifuge.

4. For red-top tubes, immediately aliquot serum into a plastic vial.

5. For serum gel tubes, the serum must be aliquoted into a plastic vial within 24 hours of collection.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Red Top
Acceptable: Yellow Top
Collect blood immediately before next scheduled dose.
Only for sustained-release formulations, collect blood a minimum of 12 hours after last dose.
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Refrigerated

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-General Request (T239)

-Therapeutics Test Request (T831)

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

Patients receiving therapeutic doses usually have lamotrigine concentrations of 3.0-15.0 mcg/mL.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring serum concentration of lamotrigine

 

Assessing compliance

 

Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine

CPT Code Information

80175

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LAMO Lamotrigine, S 6948-4

 

Result ID Test Result Name Result LOINC Value
80999 Lamotrigine, S 6948-4

Secondary ID

80999

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
National University Hospital-Singapore Additional Information:

Last updated 03/08/2026