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Mayo Clinic Laboratories

Test Code IHS Coagulation Inhibitor Screen

Important Note

Please consult haematologist before ordering this test.

Please do not order this test for patients with normal PT and APTT results, unless clinically indicated.

Laboratory Code

LAB5056

Specimen Requirements

Submit only one of the following specimens


Specimen Type: Whole Blood
Container/Tube: 3 Light Blue Top (3.2% Sodium Citrate)
Volume: 3 × 2.7 mL Whole Blood (Tubes must be full)
Collection Instructions: Send whole blood specimens to laboratory immediately.


Specimen Type: Platelet Poor Plasma
Container/Tube: 3 Light Blue Top (3.2% Sodium Citrate)
Submission Container/Tube: Plastic Vial

Minimum Volume: 3.0 mL Plasma
Collection Instructions:

1. Light blue top tube must be properly filled with whole blood.
2. Whole blood specimen should be double centrifuged and plasma separated from cells within 1 hr of collection.
3. Plasma should be separated into 3 aliquots with minimum volume of 1.0 mL each.
4. Freeze the aliquots in well-closed plastic tubes immediately.

Specimen Stability

Specimen Type Plasma
Ambient 4 hours
Refrigerate Not available
Frozen 14 days (preferred)

Methodology

APTT-Based Coagulation Test

Days and Times Performed

Monday through Friday, Office hours, TAT 5 days

Specimen Condition

Gross Haemolysis Reject
Icterus OK
Lipaemia OK
Others: Clotted or insufficient specimen Reject

Reference Interval

Absent

Testing Laboratory

National University Hospital
Haematology, 67725320

Useful For

Aid in the detection of circulating lupus anticoagulant.

Aid in the detection of coagulation inhibitors, e.g. Acquired Factor VIII inhibitor.

Service Code

12412

LOINC Code Information

50391-2

Alias

Inhibitor Screen

Non-specific Inhibitor Screen

Update

Last updated 20/03/2025