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HelpTest Code IFLCS Free Light Chains, serum
Additional Codes
| Epic Ordering Code | LAB735 |
| NBS code | LBC00411 |
| Service code | 31605 |
Specimen Requirements
Submit only one of the following:
| Preferred: | Acceptable: |
| Yellow Top | Red Top |
Processing Requirements
Allow specimen to clot for 30 mins and centrifuge within 2 hours
Specimen type: Serum
Volume: 0.5mL
Specimen Stability
| Specimen Type | Serum |
|---|---|
| Ambient | 8 hours |
| Refrigerate | 21 days (preferred) |
| Frozen | 1 month |
Specimen Condition
| Mild Haemolysis | OK |
|---|---|
| Gross Icterus | OK |
| Mild Lipaemia | OK |
| Others | Not applicable |
Methodology
Turbidimetry
Days and Times Performed
Monday, Wednesday, Thursday, TAT 2 - 5 days
Reference Interval
| Kappa FLC | 3.3 – 19.4 mg/L |
|---|---|
| Lambda FLC | 5.7 – 26.3 mg/L |
| Free Light Kappa to Lambda ratio | 0.26 – 1.65 |
In CKD patients, the free kappa: lambda ratio is: 0.37 - 3.10 (Hutchison et al. Quantitative Assessment of Serum and Urinary Polyclonal Free Light Chains in patients with Chronic Kidney Disease. Clin. J Am Soc Nephril 2008; 3: 1684 - 90).
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724399
Useful For
Elevated serum levels are associated with malignant plasma cell proliferation (e.g. multiple myeloma), lymphocytic neoplasms, Waldenstrom’s macroglobulinemia, amyloidosis and light chain deposition disease and autoimmune disease such as SLE.
Update
Last updated 17/07/2026
LOINC Code Information
| Free Light Kappa to Lambda Ratio | 48378-4 |
|---|---|
| Kappa Free Light Chains (FLC) | 36916-5 |
| Lambda Free Light Chains (FLC) | 33944-0 |