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Test Code HIVGR HIV-1 RNA Reverse Transcriptase & Protease & Integrase Genotypic Resistance

Important Note

HIV-1 viral load must be pre-determined as >2,000 copies/mL. Please refer/order 1033057 HIVL1 HIV-1 Viral Load testing (PCR, quantitative) prior to this testing, if required. HIV-1 viral load result should preferably be within 1 month.

Laboratory Code

LAB2203

Specimen Requirements

Preferred:
Specimen Type: Whole Blood
Container/Tube: Lavender Top (EDTA)
Specimen Volume: 3.0 mL x 4 tubes

Acceptable:
Specimen Type: Plasma
Container/Tube: Sterile Container
Specimen Volume: 4.0 mL

Specimen Stability

Whole Blood (EDTA) 24 hours, ambient/refrigerated (2 - 25 °C)
Plasma Frozen at -20 to -80 °C

Methodology

Reverse Transcription Polymerase Chain Reaction, High-Throughput Sequencing

Days and Times Performed

TAT 21 - 30 days

Specimen Condition

Whole Blood: Frozen or hemolysis Reject

Reference Interval

An interpretative report will be provided.

Testing Laboratory

National University Hospital
Molecular Diagnosis Centre, 67724384

Useful For

Identification of HIV-1 drug resistance mutations (DRM) associated with resistance to protease inhibitors, nucleotide reverse transcriptase inhibitors, non-nucleotide reverse transcriptase inhibitors, and integrase inhibitors.

Service Code

1033068

LOINC Code Information

80689-3

Update

Last updated 20/03/2025

Test Info

(a)  This test was developed by NUH Laboratory Medicine.

(b) This laboratory test has undergone in-house evaluation with appropriate quality assurance and control measures in line with laboratory best practice and accreditation requirements. 

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