Test Code HISER Histoplasma Antibody Complement Fixation and Immunodiffusion, Serum
Additional Codes
| Epic Ordering Code | LAB123008056 |
| NBS code | LBC06349 |
| Service code | 33604 |
Reporting Name
Histoplasma Ab CompFix/ImmDiff, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.1 mL Serum
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Yellow Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen type: Serum
Volume: 1.1 mL
Storage/transport requirements: Refrigerated
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
Special Instructions
Specimen Minimum Volume
Serum: 0.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
Method Name
Complement Fixation (CF)/Immunodiffusion (ID)
Testing Algorithm
For information see Meningitis/Encephalitis Panel Algorithm.
Day(s) Performed
Monday through Friday
Report Available
2 to 7 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
Anti-Yeast Antibody by Complement Fixation:
Negative (positive results reported as titer)
Antibody by Immunodiffusion:
Negative (positive results reported as band present)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Aiding in the diagnosis of active histoplasmosis
CPT Code Information
86698 x2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HISER | Histoplasma Ab CompFix/ImmDiff, S | 90227-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 621214 | Histoplasma Yeast CompFix, S | 20574-0 |
| 621215 | Histoplasma Immunodiffusion, S | 90232-0 |
Secondary ID
621213Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Last updated 29/07/2026