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Test Code EPO Erythropoietin, Serum

Additional Codes

Epic Ordering Code LAB873
NBS code LBC13348
Service code 31275

Reporting Name

Erythropoietin (EPO), S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL serum

Collection Instructions:

1. Morning collection, 7:30 a.m. to 12 p.m. is preferred due to diurnal variation. For more information see Cautions.

2. Centrifuge and aliquot serum into a plastic vial.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Yellow Top
Acceptable: Red Top
Morning collection, 7:30 a.m. to 12 p.m. is preferred due to diurnal variation
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen type: Serum
Volume: 0.6 mL
Storage/transport requirements: Refrigerated

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Benign Hematology Test Request (T755)

-Kidney Transplant Test Request

Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross Icterus OK

Method Name

Immunoenzymatic Assay

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

2.6-18.5 mIU/mL

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

An aid in distinguishing between primary and secondary polycythemia

 

Differentiating between appropriate secondary polycythemia (eg, high-altitude living, pulmonary disease, tobacco use) and inappropriate secondary polycythemia (eg, tumors)

 

Identifying candidates for erythropoietin (EPO) replacement therapy (eg, those with chronic kidney disease)

 

Evaluating patients undergoing EPO replacement therapy who demonstrate an inadequate hematopoietic response

CPT Code Information

82668

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EPO Erythropoietin (EPO), S 15061-5

 

Result ID Test Result Name Result LOINC Value
EPO Erythropoietin (EPO), S 15061-5

Secondary ID

80173

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
National University Hospital-Singapore Additional Information:

Last updated 17/07/2026