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Test Code DSGAB Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Additional Codes

Epic Ordering Code LAB3040811
NBS code LBC13182
Service code 36909

Reporting Name

Desmoglein 1 and 3, Serum

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Red Top
Acceptable: Yellow Top
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Refrigerated

Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Testing Algorithm

For information see Autoimmune Blistering Disease Diagnostic Algorithm.

Day(s) Performed

Varies

Report Available

1 to 10 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

Desmoglein 1:

<20 RU/mL (Negative)

≥20 RU/mL (Positive)

 

Desmoglein 3:

<20 RU/mL (Negative)

≥20 RU/mL (Positive)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Preferred screening test for patients suspected of having an autoimmune blistering disorder of the skin or mucous membranes (pemphigus)

 

Aiding in the diagnosis of pemphigus

CPT Code Information

83516 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DSGAB Desmoglein 1 and 3, Serum 94335-7

 

Result ID Test Result Name Result LOINC Value
606818 DSG 1 94336-5
606819 DSG 3 94337-3

Secondary ID

606818

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.
National University Hospital-Singapore Additional Information:

Last updated 17/07/2026