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HelpTest Code CYPAN Cytokine Panel, Plasma
Additional Codes
| Epic Ordering Code | LAB3041944 |
| NBS code | LBC12440 |
| Service code | 37136 |
Test Down Notes
Effective July 16, 2026: This test is temporarily unavailable due to analytic issues. The downtime is expected to be 2-3 months. Order LCYP as an alternative. See test notification here.
Reporting Name
Cytokine Panel, PSpecimen Type
Plasma EDTASpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Lavender-top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL Plasma
Collection Instructions:
1. Immediately after specimen collection, place the tube on wet ice.
2. Centrifuge at 4° C, 1500 x g for 10 minutes.
3. Aliquot plasma into plastic vial.
4. Within 2 hours of collection, freeze specimen.
NUH Outreach Laboratories:
Specimen Requirements
Submit the following:
Container: Purple Top
Place specimen on ice and send to lab immediately.
Processing Requirements
Centrifuge refrigerated and aliquot plasma into a Mayo plastic tube. Freeze immediately.
Specimen type: Plasma
Volume: 0.5 mL
Storage/transport requirements: Frozen
Specimen Minimum Volume
Plasma: 0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma EDTA | Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-treated specimen | Reject |
Method Name
Bead-Based Multiplex Immunoassay
Day(s) Performed
Wednesday
Report Available
2 to 8 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
Tumor necrosis factor: <10.0 pg/mL
Interleukin (IL)-6: <5.0 pg/mL
Interferon (IFN)-beta: <20.0 pg/mL
IL-10: <7.0 pg/mL
Monocyte chemoattractant protein-1: ≤198 pg/mL
IL-1 beta: <20.0 pg/mL
IFN-gamma: <60.0 pg/mL
Macrophage inflammatory protein-1 alpha: <220 pg/mL
Granulocyte-monocyte colony stimulating factor: <15.0 pg/mL
IL-2 receptor alpha soluble: ≤959 pg/mL
IFN-alpha: <20.0 pg/mL
IL-18: ≤468 pg/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Understanding the etiology of infectious or chronic inflammatory diseases, when used in conjunction with clinical information and other laboratory testing
Research studies in which an assessment of cytokine responses is needed
CPT Code Information
83520 x 10
83529
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CYPAN | Cytokine Panel, P | 82335-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 610307 | TNF | 3074-2 |
| 610308 | IL-6 | 26881-3 |
| 610309 | IFN-beta | 97051-7 |
| 610310 | IL-10 | 26848-2 |
| 610311 | MCP-1 | 97052-5 |
| 610312 | IL-1 beta | 13629-1 |
| 610313 | IFN-gamma | 27415-9 |
| 610314 | MIP-1 alpha | 97053-3 |
| 610315 | GM-CSF | 97054-1 |
| 610316 | IL-2 receptor alpha soluble | 76039-7 |
| 610317 | IFN-alpha | 33820-2 |
| 610318 | IL-18 | 33823-6 |
Secondary ID
610259Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Last updated 01/09/2026