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Test Code COM Complement, Total, Serum

Important Note

 Immediately after specimen collection, place the tube on wet ice and allow specimen to clot.

Additional Codes

Epic Ordering Code LAB3040864
NBS code LBC13419
Service code 32127

Reporting Name

Complement, Total, S

Specimen Type

Serum


Specimen Required


Patient Preparation:

Fasting: 12 hours, preferred but not required

Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL serum

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice and allow specimen to clot.

2. Centrifuge at 4° C and aliquot serum into 5 mL plastic vial.

3. Within 30 minutes of centrifugation, freeze specimen. Specimen must be placed on dry ice if not frozen immediately.

Note: If a refrigerated centrifuge is not available, it is acceptable to use a room temperature centrifuge, provided the specimen is kept on ice before centrifugation, and immediately afterward, the serum is aliquoted and frozen.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Yellow Top
Acceptable: Red Top
Patient Preparation: Fasting: 12 hours, preferred but not required
Processing Requirements
Centrifuge at 4° C and aliquot serum into a plastic vial. Freeze immediately.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Frozen

Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen 28 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Method Name

Turbidimetric Measurement of Liposome Lysis

Day(s) Performed

Monday through Friday

Report Available

1 to 2 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

≥41 U/mL

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detection of individuals with an ongoing immune process

 

First-tier screening test for congenital complement deficiencies

CPT Code Information

86162

LOINC Code Information

Test ID Test Order Name Order LOINC Value
COM Complement, Total, S 4532-8

 

Result ID Test Result Name Result LOINC Value
COM Complement, Total, S 4532-8

Secondary ID

8167

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
National University Hospital-Singapore Additional Information:

Last updated 14/07/2026