Test Code CMA Centromere Antibodies, IgG, Serum
Additional Codes
| Epic Ordering Code | LAB3041449 |
| NBS code | LBC13311 |
| Service code | 36758 |
Reporting Name
Centromere Ab, IgG, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Yellow Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial.
Specimen type: Serum
Volume: 0.5 mL
Storage/transport requirements: Refrigerated
Special Instructions
Specimen Minimum Volume
0.35 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-Treated | Reject |
Method Name
Multiplex Flow Immunoassay
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 3 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
<1.0 U (negative)
≥1.0 U (positive)
Reference values apply to all ages.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Evaluating patients with features of systemic autoimmune rheumatic disease, particularly systemic sclerosis, Sjogren’s syndrome, or overlap disease
Aiding in the phenotypic stratification of patients with systemic sclerosis (limited cutaneous vs diffuse cutaneous or risk for specific clinical manifestations)
CPT Code Information
83516
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CMA | Centromere Ab, IgG, S | 31290-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CMA | Centromere Ab, IgG, S | 31290-0 |
Testing Algorithm
For more information see Connective Tissue Disease Cascade.
Secondary ID
9278Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Last updated 14/07/2026