Cutaneous Immunofluorescence Antibodies, IgG, Serum
Reporting Name
Cutaneous Immfluor. Ab, S (IgG)For NUH patients - use Epic to order (LAB3040831)
NUH service code - 36763
Mayo test code - CIFS
Useful For
Confirming the presence of IgG antibodies to diagnose of pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Frozen | 30 days | ||
Ambient | 14 days |
Reference Values
Report includes presence and titer of circulating antibodies. If serum contains basement membrane zone antibodies on split-skin substrate, patterns will be reported as:
1) Epidermal pattern, consistent with pemphigoid
2) Dermal pattern, consistent with epidermolysis bullosa acquisita
Negative in normal individuals
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
88346
88350
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CIFS | Cutaneous Immfluor. Ab, S (IgG) | 104835-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
21539 | Cell Surface Ab IgG | 104831-3 |
21540 | Basement Membrane IgG | 104836-2 |
21541 | Primate Esophagus IgG | 66881-4 |
21542 | Primate Split Skin IgG | 104832-1 |
21638 | Other | 48767-8 |
Report Available
2 to 7 daysReject Due To
Gross hemolysis | OK |
Gross lipemia | Reject |
Gross icterus | OK |
Method Name
Indirect Immunofluorescence
Secondary ID
8052Updated on 21/03/2022