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HelpTest Code CIFS Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum
Additional Codes
| Epic Ordering Code | LAB3040831 |
| NBS code | LBC13181 |
| Service code | 36763 |
Reporting Name
Cutaneous Immfluor. Ab, IgG/IgG4, SSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Yellow Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a Mayo plastic tube.
Specimen type: Serum
Volume: 2 mL
Storage/transport requirements: Refrigerated
Special Instructions
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Indirect Immunofluorescence Assay (IFA)
Testing Algorithm
If IgG anti-cell surface or anti-basement membrane zone antibodies are present, then the IgG antibody titer will be reflexed and performed at an additional charge.
For more information see Autoimmune Blistering Disease Diagnostic Algorithm.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CIFST | CIFS Titer, IgG, S | No | No |
Day(s) Performed
Monday through Friday
Report Available
2 to 7 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
Negative
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Confirming the presence of IgG and/or IgG4 antibodies to diagnose pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus
CPT Code Information
88346
88350
88350 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CIFS | Cutaneous Immfluor. Ab, IgG/IgG4, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 21539 | Cell Surface Ab IgG | 93233-5 |
| 21540 | Basement Membrane IgG | 29994-1 |
| 21542 | Primate Split Skin IgG | 104832-1 |
| 622319 | Cell Surface Ab IgG4 | In Process |
| 622320 | Basement Membrane IgG4 | In Process |
| 622322 | Primate Split Skin IgG4 | In Process |
| 21638 | Other | 48767-8 |
Secondary ID
8052Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Last updated 16/07/2026