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Test Code BHYD Beta-Hydroxybutyrate, Serum

Important Note

Sample only has 7 days stability to reach Mayo Laboratories – referring hospital laboratory should contact NUH Laboratory for feasibility.

Additional Codes

Epic Ordering Code LAB3053162
NBS code LBC00129
Service code 36791

Reporting Name

Beta-Hydroxybutyrate, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Gold Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial within 2 hours.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Frozen

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 7 days
  Refrigerated  7 days

Reject Due To

Gross hemolysis Reject

Method Name

Photometric, B-Hydroxybutyrate Dehydrogenase (B-HBDH)

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

<0.4 mmol/L

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring therapy for diabetic ketoacidosis

 

Investigating the differential diagnosis of any patient presenting to the emergency room with hypoglycemia, acidosis, suspected alcohol ingestion, or an unexplained increase in the anion gap

 

In pediatric patients, the presence or absence of ketonemia/uria is an essential component in the differential diagnosis of inborn errors of metabolism

 

Serum beta-hydroxybutyrate is a key parameter monitored during controlled 24-hour fasts

CPT Code Information

82010

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BHYD Beta-Hydroxybutyrate, S 6873-4

 

Result ID Test Result Name Result LOINC Value
BHYD Beta-Hydroxybutyrate, S 6873-4

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
National University Hospital-Singapore Additional Information:

Last updated 30/06/2026