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HelpTest Code APGH Alpha-Subunit Pituitary Tumor Marker, Serum
Additional Codes
| Epic Ordering Code | LAB230 |
| NBS code | LBC13301 |
| Service code | 36757 |
Reporting Name
AlphaSubunit Pituitary Tumor MarkerSpecimen Type
SerumOrdering Guidance
This test should not be ordered on pregnant patients.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
NUH Outreach Laboratories:
Specimen Requirements
Submit the following:
Preferred: Gold Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Frozen
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.
Specimen Minimum Volume
Serum: 0.35 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen (preferred) | 90 days |
| Refrigerated | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Immunochemiluminescent Assay
Day(s) Performed
Friday
Report Available
2 to 8 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
PEDIATRIC
≤5 days: ≤50 ng/mL
6 days-12 weeks: ≤10 ng/mL
3 months-17 years: ≤1.2 ng/mL
Tanner II-IV*: ≤1.2 ng/mL
ADULTS
Males: ≤0.5 ng/mL
Premenopausal females: ≤1.2 ng/mL
Postmenopausal females: ≤1.8 ng/mL
Pediatric and adult reference values based on Mayo studies.
*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (±2) years and for girls at a median age of 10.5 (±2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Adjunct in the diagnosis of pituitary tumors
As part of the follow-up of treated pituitary tumor patients
Differential diagnosis of thyrotropin-secreting pituitary tumor versus thyroid hormone resistance
Differential diagnosis of constitutional delay of puberty versus hypogonadotrophic hypogonadism
CPT Code Information
82397
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| APGH | AlphaSubunit Pituitary Tumor Marker | 14170-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 9003 | AlphaSubunit Pituitary Tumor Marker | 14170-5 |
Secondary ID
9003Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Last updated 10/06/2026