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HelpTest Code ANCA Anti-Neutrophil Cytoplasmic Antibody (ANCA)
Additional Codes
| Epic Ordering Code | LAB458 |
| NBS code | LBC04423 |
| Service code | 32303 |
Specimen Requirements
Submit only one of the following:
| Preferred: | Acceptable: |
| Yellow Top | Red Top |
Processing Requirements
Allow specimen to clot for 30 mins and centrifuge within 2 hours
Specimen type: Serum
Volume: 0.5mL
Specimen Stability
| Specimen Type | Serum |
|---|---|
| Ambient | 2 days |
| Refrigerate | 2 weeks (preferred) |
| Frozen | 1 year |
Specimen Condition
| Haemolysis | OK |
|---|---|
| Icterus | OK |
| Lipaemia | OK |
| Others | Not applicable |
Methodology
Enzyme Immunoassay
Days and Times Performed
Thursday, TAT 2 - 8 days
Reference Interval
MYPO:
No antibody detected: < 20 U/mL
Positive: ≥ 20 U/ml
PR3:
No antibody detected: < 20 U/mL
Positive: ≥ 20 U/mL
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724346
Useful For
Clinical Usage Autoantibodies against neutrophil cytoplasmic antigens have been found in patients with Wegener’s ranulomatosis, a disease associated with a necrotising granulomatous vasculitis affecting the upper and lower respiratory tract and the kidney. These antibodies have also been observed in microscopic polyarthriitis, SLE and vasculitis. They correlate best in individuals with a necrotising crescentic glomerulonephritis, with or without systemic complications.
Update
Last updated 16/07/2026
LOINC Code Information
| MYPO | 48404-8 |
|---|---|
| PR3 | 74106-6 |
Alias
Antineutrophil Cytoplasmic Antibodies (ACPA)
Cytoplasmic Neutrophilic Ab
MPO/PR-3 (ANCA)
Panel Information
Panel includes the following tests:
- Anti-Myeloperoxidase IgG
- Anti-Proteinase 3 IgG