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HelpTest Code ADALP Adalimumab Quantitative with Antibody, Serum
Additional Codes
| Epic Ordering Code | LAB3041061 |
| NBS code | LBC13178 |
| Service code | 36905 |
Reporting Name
Adalimumab QN with Antibodies, SSpecimen Type
SerumOrdering Guidance
If there is a known justification for performing both quantitation and antibody levels, this is the correct test to order. If there is not a known reason to perform the adalimumab antibody component, consider ADALX / Adalimumab Quantitative with Reflex to Antibody, Serum. ADALX testing begins with adalimumab quantitation and testing for adalimumab antibodies is only performed when the quantitation results are 8.0 mcg/mL or less.
Specimen Required
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.4 mL Serum
Collection Instructions:
1. Draw blood immediately before the next dose of drug administration (trough specimen).
2. Centrifuge and aliquot serum into a plastic vial.
NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Gold Top
Acceptable: Red Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial.
Specimen type: Serum
Volume: 0.4 mL
Storage/transport requirements: Refrigerated
Forms
If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.
Special Instructions
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
| Heat-treated specimens | Reject |
Method Name
QNADL, ABADL: Enzyme-Linked Immunosorbent Assay (ELISA)
INTAD: Technical Interpretation
Day(s) Performed
Monday, Wednesday, Friday
Report Available
3 to 6 daysPlease note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.
Reference Values
ADALIMUMAB QUANTITATIVE:
Limit of quantitation is 0.8 mcg/mL. Optimal therapeutic ranges are disease specific.
ADALIMUMAB ANTIBODY:
<14.0 AU/mL
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Therapeutic drug monitoring of adalimumab
Evaluating patients for loss of response, partial response on initiation of therapy, autoimmune or hypersensitivity reactions, primary nonresponse, reintroduction after drug holiday, endoscopic/computed tomography enterography recurrence (in inflammatory bowel disease), acute infusion reactions and proactive monitoring
This test does not differentiate between the originator and biosimilar products.
CPT Code Information
80145
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ADALP | Adalimumab QN with Antibodies, S | 99781-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| QNADL | Adalimumab QN, S | 86894-3 |
| ABADL | Adalimumab Ab, S | 90779-0 |
| INTAD | Adalimumab Interpretation | 77202-0 |
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| QNADL | Adalimumab QN, S | Yes, (ADALX) | Yes |
| ABADL | Adalimumab Ab, S | No | Yes |
| INTAD | Adalimumab Interpretation | No | Yes |
Testing Algorithm
For information see Ulcerative Colitis and Crohn Disease Therapeutic Drug Monitoring Algorithm.
Secondary ID
620309Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Last updated 22/06/2026