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Test Code A4AB Aquaporin-4 (AQP-4) Antibodies

Laboratory Code

LAB3041004

Specimen Requirements

Specimen Type: Serum
Container/Tube: Red Top
Volume: 6.0 mL
Minimum Volume: 0.5 mL serum
Collection Instructions: Allow specimen to clot for 30 mins and centrifuge within 2 hrs

Specimen Stability

Specimen Type Serum
Ambient  3 days
Refrigerate 2 weeks (preferred)
Frozen 1 year

Methodology

Immunofluorescence

Days and Times Performed

Alternate Tuesday, TAT 1 - 15 days

Specimen Condition

Haemolysis OK
Icterus OK
Lipaemia OK
Others Not applicable

Reference Interval

Negative

Testing Laboratory

National University Hospital

Clinical Chemistry, 67724346

Useful For

Neuromyelitis Optica (NMO) is an immune-mediated demyelinating disease of the central nervous system (CNS) characterized by optic neuritis and transverse myelitis. Presence of Aquaporin-4 antibodies is highly specific for NMO.

Service Code

33310

LOINC Code Information

63439-4

Alias

AQP4
Aquaporin
Devic's Antibody
NMO (Neuromyelitis Optica)
NMO-IgG
Optic Neuritis Antibody

Update

Last updated 21/02/2025