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HelpTest Code A4AB Aquaporin-4 (AQP-4) Antibodies
Specimen Requirements
Specimen Type: Serum
Container/Tube: Red Top
Volume: 6.0mL
Minimum Volume: 0.5mL serum
Collection Instructions: Allow specimen to clot for 30 minutes and centrifuge within 2 hours
Sample Stability
** Preferred temperatures for storage prior to and during shipping to NUH **
| Specimen Type: | Serum |
|---|---|
| Ambient: | 3 days |
| Refrigerate: | 2 weeks |
| Frozen: | 1 year |
Reference Interval
Negative
Days and Times Performed
Alternate Tuesday, TAT 1–15 days
Methodology
Immunofluorescence
Service Code
0033310
Update
Last updated 26/02/2022
Unacceptable Condition
| Haemolysis: | NA |
|---|---|
| Icterus: | NA |
| Lipaemic: | NA |
| Others: | NA |
Testing Laboratory
National University Hospital
Clinical Chemistry, 67724346
Alias
AQP4
Aquaporin
Devic's Antibody
NMO (Neuromyelitis Optica)
NMO-IgG
Optic Neuritis Antibody
Useful For
Neuromyelitis Optica (NMO) is an immune-mediated demyelinating disease of the central nervous system (CNS) characterized by optic neuritis and transverse myelitis. Presence of Aquaporin-4 antibodies is highly specific for NMO.