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Test Code 21OH 21-Hydroxylase Antibodies, Serum

Additional Codes

Epic Ordering Code LAB3041103
NBS code LBC12436
Service code 36768

Reporting Name

21-Hydroxylase Ab, S

Specimen Type

Serum


Ordering Guidance


Testing for autoantibodies against 21-hydroxylase is recommended following confirmation of adrenal insufficiency to help differentiate between causes of primary adrenal insufficiency



Shipping Instructions


Ship specimen frozen on dry ice



Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial to remove from cells or gel prior to shipping.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Red Top
Acceptable: Yellow Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial to remove from cells or gel prior to shipping.
Specimen type: Serum
Volume: 1 mL
Storage/transport requirements: Frozen

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen 14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Day(s) Performed

Wednesday

Report Available

3 to 9 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

Negative

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Investigating adrenal insufficiency

 

Aiding in the detection of those at risk of developing autoimmune adrenal failure in the future

CPT Code Information

83516

LOINC Code Information

Test ID Test Order Name Order LOINC Value
21OH 21-Hydroxylase Ab, S 85363-0

 

Result ID Test Result Name Result LOINC Value
607788 21-Hydroxylase Ab, S 85363-0

Secondary ID

607788

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
National University Hospital-Singapore Additional Information:

Last updated 29/06/2026