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Test Code 21DOC 21-Deoxycortisol, Serum

Important Note

Morning (8 a.m.) specimen is preferred.

Additional Codes

Epic Ordering Code LAB3041956
NBS code LBC11816
Service code 37148

Reporting Name

21-Deoxycortisol, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Morning (8 a.m.) specimen is preferred.

2. Centrifuge and aliquot serum into a plastic vial.


National University Hospital-Singapore Note:

NUH Outreach Laboratories:
Specimen Requirements
Submit only one of the following:
Preferred: Red Top
Acceptable: Yellow Top
Processing Requirements
Centrifuge and aliquot serum into a plastic vial.
Specimen type: Serum
Volume: 0.5 mL
Storage/transport requirements: Refrigerated

Special Instructions

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 21 days
  Frozen  21 days
  Ambient  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Day(s) Performed

Tuesday

Report Available

3 to 10 days
National University Hospital-Singapore Note:

Please note that this is a referral test requiring transport to the external testing facility and an additional 3-5 days is required.

Reference Values

<5.0 ng/dL

Reference values apply to all ages.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

As an adjunct to measurement of 17-hydroxyprogesterone, androstenedione, and cortisol in the diagnosis of difficult cases of suspected 21-hydroxylase (CYP21A2) deficiency

 

Identifying heterozygote CYP21A2 deficiency carriers

 

As an adjunct to measurements of 17-hydroxyprogesterone, androstenedione, testosterone, and, in female patients, estradiol in the follow-up of children with CYP21A2 deficiency

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
21DOC 21-Deoxycortisol, S 74872-3

 

Result ID Test Result Name Result LOINC Value
89477 21-Deoxycortisol, S 74872-3

Secondary ID

89477

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
National University Hospital-Singapore Additional Information:

Last updated 29/06/2026